The LEx (Life Extension) Prize




The LEx (Life Extension) Prize is a US $1 Million cash prize to be awarded to the first researcher(s) or scientist(s) who accomplish the goal of reliably demonstrating the reversal or halting of the aging process in humans, as defined by The LEx Prize Criteria.  The winning scientists or researchers must demonstrate that the therapeutic program has reduced the objective, measurable biomarkers of aging in twenty (20) human subjects (ages 70 years or more), by twenty (20) years each.   

For the purposes of The LEx Prize, the biomarkers of aging to be satisfactorily reversed include, but are not limited to:*
Laboratory Markers:
Mitrochondrial energy production
Production of intrinsic intracellular antioxidant molecules (demonstrating antioxidant protection/buffering capacity)
Collagen crosslinking histology; intracellular matrix changes secondary to aging effects of connective tissue
Cortisol levels and diurnal variation
DNA repair levels and restoration of telomere length

Physical Markers:
Body composition and body fat
Bone density
EKG, R1-R2 variability, and response to stress and load
Peripheral vascular circulation
Cardiac output
Pulmonary function
Brachial/popliteal and femoral pulse pressures
Kidney filtration/renal function
Grip strength
Memory and cognitive function, and timed test-taking performance
Psychological disposition
Nerve conduction velocity
Sensory function: including olfactory, taste, hearing, tactile, visual accommodation, and vibrational sense
Balance and coordination
Reaction time
*Criteria may be revised at the sole discretion of The LEx Prize Scientific Panel to reflect updated knowledge on the process of aging.

Scientists or researchers interested in claiming The LEx Prize must register with the Prize Review Committee in-advance of preparing their submission.  Complete the Contact Form to register and to receive the complete Prize Requirements.  

For consideration in claiming The LEx Prize, scientists or researchers will be required to submit a complete and thorough written presentation of their work.  The presentation shall include scientific demonstration and independently verifiable data showing that the therapeutic intervention program has reversed the objective biomarkers of aging as described within the Criteria.  

We gratefully acknowledge the generous contributions of prominent physicians, scientists, and patrons of the anti-aging medical movement.  Leading individual LEx Prize pledges received to-date include:
US $100,000 from A4M Chairman Robert Goldman, MD, PhD, DO, FAASP
US $100,000 from A4M President Ronald Klatz, MD, DO
US $100,000 from Sam Weaver, PhD and Carol Weaver, Ed.D.
US $25,000 from Eric Braverman, MD
US $25,000 from Ron Rothenberg, MD
US $25,000 from Mark Gordon, MD
US $10,000 from Nick Delgado, PhD
US $  5,000 from Catherine Cebula
With your support, we can make The LEx Prize a success, and the reversal of aging a reality. Use the Contact form to submit your pledge to this important project.